sh-Oligopeptide-1 Solution

A recombinant signal protein, ready in liquid form

EGF is one of the best-known biotech names in premium skin care, and this listing supplies it as a ready solution. Its INCI is sh-Oligopeptide-1, where the "sh" prefix marks a synthetic human-identical sequence produced by recombinant biotechnology. The published CAS for the peptide is 62253-63-8. The full vehicle, including water and any stabilizer or preservative, is confirmed on the CoA for each lot. Because the active arrives already dissolved, you avoid weighing microgram amounts of a dry protein, which is the hardest part of working with recombinant actives on a small bench.

How it differs from expression-line peptides

An older template on this page framed EGF as an Acetyl Hexapeptide-8-class peptide. That was wrong. Acetyl Hexapeptide-8 Solution is Acetyl Hexapeptide-8, a short synthetic peptide marketed for the look of expression lines. EGF is a much larger recombinant polypeptide with a renewal and radiance story. They can sit in the same serum, but they are not substitutes. Our peptide solutions list both, and the powder grades on our peptide powders list are separate SKUs with its own CoA.

Handling a recombinant protein

Temperature and shear

Proteins are more fragile than short peptides. Add it in cool-down, below 40 °C, with gentle mixing, and avoid long holds at high temperature. Avoid high-shear homogenizing after the protein is in, and stir it in with a paddle or by hand.

Level and pH

Take the use level from the supplier documentation for your lot. Keep the finished product in a mild range and avoid strong acid exfoliants or high levels of free alcohol in the same product, both of which can denature proteins.

Product types that suit it

Ampoules, light serums, sheet-mask essences and lightweight gel creams are the usual homes for EGF. Simple, low-surfactant bases give a protein the best chance of staying intact. Rich creams with many emulsifiers can work, but test them for stability with the protein in place.

Pairing ideas

Sodium hyaluronate, glycerin, panthenol and a gentle humectant system make a clean background. Niacinamide and ceramides suit barrier-minded creams. Add each active separately and check clarity, odor and viscosity after each addition instead of premixing several actives in one beaker.

Example serum architecture

Water, glycerin, a sodium hyaluronate gel, a mild preservative system, a chelator, and EGF solution at the level the supplier documentation names. No gram recipe is given here because the level comes from the CoA. Fill into airless pumps or dark glass droppers to limit air and light.

Claims

Talk about skin that looks smoother, fresher and more even. Keep claims cosmetic and tied to appearance. Any before-and-after statement needs a test on the finished product, not on the raw material.

Testing the finished product

Run a stability check on the finished product at room temperature, at 40 °C and in a fridge for several weeks, and watch color, odor, clarity, viscosity and pH. Check the product in its final pack too, since pumps, droppers and jars expose it to air differently. A preservative challenge test on the final product is the standard step before launch.

Lot handling and storage

Record appearance and pH on arrival, compare them with the CoA, and keep the CoA with your batch records so each finished batch can be traced to its lot. Recombinant actives are often shipped and stored cold; follow the storage line on the CoA, and keep the bottle closed between uses.

Ordering

It is sold as a raw material for cosmetic formulation, not as a finished consumer product. Start with a small pack for bench trials and scale once your stability checks pass. It ships from Florida, usually within 1 to 2 business days, in the pack sizes shown above, and US shipping is free on orders of $50 or more.