Tetrapeptide-30 Solution

What Tetrapeptide-30 is

Tetrapeptide-30 is a short peptide developed to balance skin tone. There are several ways to brighten the skin: reducing the activity of tyrosinase, blocking the transfer of melanin into skin cells, or calming the activation of melanocytes, the cells that make pigment. Tetrapeptide-30 is thought to work by reducing the amount of tyrosinase and calming melanocyte activation. This solution delivers it ready to use in glycerin and water, so it adds a brightening peptide to a formula without any powder handling.

It sits with the ready peptide liquids in our peptide solutions section. For a tone peptide with a different mechanism, compare it with Melanostatine 5, which works on the signal that triggers pigment production.

Composition and label INCI

The INCI is Tetrapeptide-30, Glycerin, Water. The peptide content is 1600 ppm, and the solution is a colorless, clear, viscous liquid. The only component with its own CAS number given by the supplier is glycerin, 56-81-5.

What testing shows

In skin studies reported by the manufacturer, the peptide reduced the yellow tone of the skin from four weeks and faded the look of age spots after eight weeks. Overall appearance improved after two weeks and the evenness of skin tone after four weeks. The manufacturer also reports a clear boost in performance when it is combined with sodium ascorbyl phosphate, a vitamin C derivative. It is described as skin-friendly, suitable for all skin types and soothing.

How to use it

For oil-in-water creams and lotions, add it during cooling below 40 °C, or directly to the water phase in a cold process. For water-in-oil emulsions, add it before homogenization below 30 °C, or to the water phase in a cold process. The solution is water-soluble.

Pairing ideas

Tetrapeptide-30 works well with vitamin C derivatives, niacinamide and alpha arbutin in even tone serums. It suits hand creams, décolleté products, appearance-focused cosmetic creams that target age spots and products for deeper skin tones where an even look is the main goal. Combine it with a daily sun care step in the routine for the most visible tone results.

Why a peptide for tone

Many brightening actives are acids or reducing agents that can sting, discolor or need a narrow pH. A peptide solution is colorless, odorless and easy to dose, and it blends into almost any water-based product. That makes Tetrapeptide-30 a practical way to add a tone claim to a moisturizer or serum that already has its texture worked out, without reformulating the base.

Bench example: even tone serum

This 100 g bench batch shows one way to use the material. Weigh 82.5 g distilled water and dissolve 4 g niacinamide in it. Add 4 g glycerin, 2 g propanediol and 0.5 g hydroxyethylcellulose, and stir until it hydrates into a light gel. Below 40 °C, add 2.5 g Tetrapeptide-30 solution, 2 g sodium ascorbyl phosphate predissolved in 1.5 g water, and 1 g broad-spectrum preservative used at its supplier rate. Check that the pH sits between 6.0 and 6.5, which suits the vitamin C derivative, and fill into airless pumps.

Where it fits in a product line

Tetrapeptide-30 is a good peptide lead for brightening ranges that want an alternative to strong acid peels.

Storage

For long term storage, keep the container tightly closed in the refrigerator at about 4 °C. Close the pack quickly after each use. For cosmetic formulation use only.