Acetyl Tetrapeptide-5 Solution, IO

Acetyl Tetrapeptide-5 Solution is the trade name for Acetyl Tetrapeptide-5. The same INCI is also available as Acetyl Tetrapeptide-5 powder.

An eye-contour peptide

Acetyl Tetrapeptide-5 Solution is a water-soluble solution of Acetyl Tetrapeptide-5, CAS 820959-17-9, made for eye gels, eye serums and under-eye creams. Brands use it when a product brief talks about the look of under-eye puffiness and a smoother, fresher-looking eye contour. Because it arrives as a liquid, it can be added straight into a cool water phase.

INCI and documents

The active INCI is Acetyl Tetrapeptide-5. Confirm the full vehicle INCI and active content on the CoA for each lot. This card does not state a use percentage; follow the supplier documentation.

How to formulate an eye gel

Base choice

Eye products need a light, fast-absorbing base. A clear water-gel thickened with a skin-friendly polymer, a fluid serum or a light emulsion all work. Keep fragrance out and choose a mild, validated preservative system for the eye area.

Adding the peptide

Add Acetyl Tetrapeptide-5 Solution during cool-down, below 40 °C, with gentle mixing. Avoid prolonged heat afterward. Check pH, clarity and viscosity in the finished gel.

Pairing ideas for the eye area

Acetyl Tetrapeptide-5 is often combined with humectants such as Hyaluronic Acid Liquid for a cushioned feel, and with an expression-line peptide such as Acetyl Octapeptide-3 Solution when the brief also covers crow's feet. Botanical hydrators like Tamarind Seed Extract add a light film. Add each active separately in cool-down.

Claims and positioning

Keep wording cosmetic: the look of puffiness, a smoother-looking eye contour, a refreshed look. Cooling packaging, such as a metal roller tip, can support the sensory story without extra claims.

Eye-area formulating checklist

The skin around the eyes is thin, so a gentle base matters as much as the active. Keep the pH close to skin-neutral, avoid fragrance and strong solvents, and choose a preservative system validated for leave-on eye products. Check the gel for clarity, pH and viscosity before and after the peptide addition, and run stability in the final packaging at room temperature and at 40 °C.

Texture

A thin, slightly cooling gel suits a morning product; a light emulsion suits night use. Small amounts of humectant keep the gel from drying to a tacky film.

Storage

Keep the solution tightly closed, cool and away from light, and refrigerate opened material where practical. Respect the shelf life on the CoA.

Sample eye-gel architecture

A typical eye gel combines water, a humectant such as glycerin, a gentle gel-forming polymer, Acetyl Tetrapeptide-5 Solution and a second active such as hyaluronic acid, plus a preservative validated for the eye area. Exact levels come from the supplier documentation for each ingredient, so build the first lab batch from those documents and adjust texture from there. A metal roller tip or a soft-touch tube suits the format.

Ordering

Acetyl Tetrapeptide-5 Solution is sold for professional cosmetic formulation, not as a finished eye product. It ships from Florida, usually within 1 to 2 business days, in the pack sizes shown above, and US shipping is free on orders of $50 or more. Browse more eye-area and expression-line actives in our peptide solutions section.