Acetyl Octapeptide-3 Solution, IO

Acetyl Octapeptide-3 Solution is the trade name for Acetyl Octapeptide-3, sometimes shortened to octapeptide-3 or acetyl octapeptide.

Acetyl Octapeptide-3 Solution at a glance

Acetyl Octapeptide-3 Solution is the trade name formulators use for Acetyl Octapeptide-3, an eight-amino-acid peptide that extends the Acetyl Hexapeptide-8 sequence by two residues. It belongs to the same expression-line family as Acetyl Hexapeptide-8 and is chosen for serums, eye gels and creams whose claims center on the look of forehead lines and crow's feet. This listing is a water-soluble solution, so it goes straight into the cool-down phase without a dissolving step.

Composition and documents

The active is Acetyl Octapeptide-3. The vehicle is typically water plus a preservative, and the full INCI, appearance and active content are confirmed on the CoA that comes with each lot. CAS is shown as N/A on this page because the solution is a mixture; ask for the CoA if your regulatory file needs the active's identifiers. Dose the solution to the in-use level of Acetyl Octapeptide-3 stated in the supplier documentation, starting at the supplier recommendation.

How to add Acetyl Octapeptide-3 Solution

Process step

Add Acetyl Octapeptide-3 Solution in the water phase during cool-down, below 40 °C, and mix gently. Avoid holding the batch hot after addition and avoid strong shear. In emulsions, add after the emulsion has formed and cooled.

Base and pH

Clear water-gels, light serums and eye gels are the easiest bases. Check the final pH and clarity in your own system, and validate the preservative system for the finished formula rather than relying on the vehicle preservative.

Building an expression-line serum

Acetyl Octapeptide-3 Solution is often layered with Acetyl Hexapeptide-8 Amplified Solution so the formula carries both the hexapeptide and the octapeptide, each at a moderate level. A matrikine such as Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7 Liquid can be added when the brief also mentions firmness. Humectants such as glycerin or hyaluronic acid give the serum slip and a comfortable finish, which matters for a product applied around the eyes. Keep claims cosmetic: smoother-looking skin and the look of expression lines.

Lab checklist for Acetyl Octapeptide-3 Solution serums

Record pH and viscosity before and after adding the peptide, and keep the final pH within the working range of your preservative. If clarity changes, look first at thickeners and electrolytes added afterward. Run stability in the final packaging at room temperature and 40 °C, checking appearance, odor and pH over several weeks.

Storage and handling

Keep the solution tightly closed in a cool, dark place and refrigerate opened material where practical. Use clean tools, close the bottle quickly and respect the shelf life on the CoA.

Documents

Each lot ships with a CoA. Keep it with your batch records, since it is the reference for active content, appearance and the full INCI.

Which Acetyl Octapeptide-3 Solution listing should I buy?

The catalog also carries Acetyl Octapeptide-3 Solution peptide solution C, a concentrate with its own published INCI and use range, and a powder grade for labs that work from neat peptide. Solution and powder strengths are not interchangeable, so recalculate your formula when you switch grades. It ships from Florida, usually within 1 to 2 business days, in the pack sizes shown above, and US shipping is free on orders of $50 or more. Compare all peptide solutions.