Acetyl Tetrapeptide-5 Powder

Acetyl Tetrapeptide-5 is the INCI name of the peptide sold as Acetyl Tetrapeptide-5.

The under-eye peptide, dry

Acetyl Tetrapeptide-5 is the peptide most brands reach for when the brief is under-eyes that look less puffy. It is widely known by the trade name Acetyl Tetrapeptide-5. The INCI is Acetyl Tetrapeptide-5 and the CAS is 820959-17-9. This listing is the powder, which suits teams that want to set their own concentration in the premix rather than buy a ready liquid.

Powder and solution

Acetyl Tetrapeptide-5 Solution, for example SKU T60011, is the liquid form on our peptide solutions list. Keep each specification's CoA with its own SKU. For a multi-active eye product, Hesperidin Methyl Chalcone + Dipeptide-2 + Palmitoyl Tetrapeptide-7 Eye Complex adds two more peptides and a flavonoid derivative.

Working with the powder

Dissolving

Weigh the powder on a calibrated balance, dissolve it completely in a small portion of the formula water before it meets the rest of the batch, and add that premix in cool-down, below 40 °C. Check that the premix is fully clear before you add it.

Compatibility

Keep it away from strong oxidizers and high-ionic-strength systems, such as products very rich in salts. A mild, water-rich base is the safest home.

Level

Take the use level from the supplier documentation for your lot.

Product types that suit it

Eye gels, roll-on eye serums, eye creams, under-eye patches and light eye emulsions.

Pairing ideas

Caffeine, panthenol, sodium hyaluronate and Dipeptide-2 complexes. Add each active separately and check clarity, odor and viscosity after each addition instead of premixing several actives in one beaker.

Example architecture

Water, glycerin, a light carbomer gel, caffeine, the Acetyl Tetrapeptide-5 premix at the supplier level, a chelator and a mild preservative, filled into a metal roll-on. The level comes from the CoA, so no gram recipe is shown here.

Claims

Describe under-eyes that look less puffy, smoother and more rested with regular use. Keep claims cosmetic and tied to appearance. Any before-and-after statement needs a test on the finished product, not on the raw material.

Testing the finished product

Run a stability check on the finished product at room temperature, at 40 °C and in a fridge for several weeks, and watch color, odor, clarity, viscosity and pH. Check the product in its final pack too, since pumps, droppers and jars expose it to air differently. A preservative challenge test on the final product is the standard step before launch.

Lot handling and storage

Record appearance and pH on arrival, compare them with the CoA, and keep the CoA with your batch records so each finished batch can be traced to its lot. Keep the powder tightly closed and dry, since peptides pick up moisture from the air, and respect the shelf life on the CoA.

Labeling and documents

Write the INCI exactly as the CoA for your lot gives it, in the order the supplier lists it, and keep the CAS line the same as the CoA, including N/A or Mixture where that is what it says. Keep the CoA with your batch records. If your market needs an SDS or a full ingredient breakdown, ask for it before you scale so the paperwork matches the batch you buy.

Ordering

It is sold as a raw material for cosmetic formulation, not as a finished consumer product. Start with a small pack for bench trials and scale once your stability checks pass. It ships from Florida, usually within 1 to 2 business days, in the pack sizes shown above, and US shipping is free on orders of $50 or more.