Acetyl Hexapeptide iposome

Argireline-class peptide in liposomes

This liquid carries Acetyl Hexapeptide-8, the best-known expression-line peptide, inside liposomes: tiny lipid vesicles that hold water-soluble actives. Liposomal grades are chosen when a brand wants a delivery story and a slightly richer, milky look in the finished serum. CAS is Mixture; the peptide itself is listed as 616204-22-9. Stored notes describe a cloudy liquid, which is normal for liposomes. The CoA confirms the full INCI for each lot, including the lipids that form the vesicles.

Compared with the plain solutions

The classic Argireline solution and the INCI-named Acetyl Hexapeptide-8 solution carry the same peptide without liposomes. They give a clear serum and are easier to work with in complex systems. Choose this liposomal grade from our peptide solutions when the delivery story matters.

Formulating with liposomes

Phase and temperature

Add it in cool-down, below 40 °C, with gentle mixing, and avoid long holds at high temperature. Liposomes are delicate: heat, strong shear, high alcohol and strong surfactants can break the vesicles.

Mixing

Stir gently with a paddle rather than a high-shear mixer. Add the liposomes as one of the last steps, after any thickener has hydrated and after the emulsion, if any, has formed and cooled.

Level

This card does not state a use percentage, so follow the CoA and the supplier documentation for the level.

Product ideas

Eye serums, forehead serums, light gel-creams, sheet-mask essences and night creams. The cloudy look suits milky serums and essences better than crystal-clear gels.

Pairing ideas

Pentapeptide-18 and Acetyl Octapeptide-3 extend the expression-line story. Hyaluronic acid and glycerin support a plumper look. Avoid high levels of ethanol and strong cleansing surfactants in the same product, because they can disrupt liposomes.

Example: liposomal eye serum architecture

Water, glycerin, a pre-hydrated thin gel, the liposomal peptide added last with gentle stirring, panthenol and a preservative suited to eye products. Levels follow the supplier documentation. A dropper or roller bottle suits the texture.

Claims

Keep claims cosmetic: expression lines look softer and skin looks smoother after regular use. A liposome claim should match the material on the CoA. Do not compare the product with injections.

Lot handling and storage

Record appearance and pH on arrival, compare them with the CoA, and keep the CoA with your batch records so each finished batch can be traced to its lot. Store tightly closed, cool and away from light. Do not freeze, because freezing can damage liposomes.

Stability checks before scale-up

Run a small pilot batch first. Keep samples at room temperature, in a warm cabinet and in the fridge, and check color, odor, clarity, viscosity and pH at set intervals over several weeks. Test the product in the final pack as well as in glass, because pumps, droppers and tubes can change how a peptide product ages. Write every observation into the batch record next to the lot number of the raw material.

Ordering

It ships from Florida, usually within 1 to 2 business days, in the pack sizes shown above, and US shipping is free on orders of $50 or more.