Acetyl Hexapeptide-8 Solution

Acetyl Hexapeptide-8, formerly listed as Acetyl Hexapeptide-3, is the INCI name of this expression-line peptide.

The expression-line peptide, sold under its INCI name

Some buyers want the trade name on the label; others want only the INCI. This listing is for the second group. It is Acetyl Hexapeptide-8 in solution, the same active class as the well-known Acetyl Hexapeptide-8 trade solutions, but listed by its INCI name. The published CAS is 616204-22-9. The full vehicle INCI is confirmed on the CoA for each lot, so check it before you write your ingredient list.

How this SKU relates to the others

We list several pages in this family, and they are separate products with separate CoAs. Classic Acetyl Hexapeptide-8 Solution is the trade-name solution. Acetyl Hexapeptide-8 Amplified Solution is a higher-strength grade. Acetyl Octapeptide-3 Solution is Acetyl Octapeptide-3, a longer peptide, not this hexapeptide. If you have already tested a formula with one grade, switching to another means a new stability check. The whole range is in our peptide solutions.

Formulating with Acetyl Hexapeptide-8

Phase and temperature

Add it in cool-down, below 40 °C, with gentle mixing, and avoid long holds at high temperature. It is water-soluble and blends into serums, gels, toners and finished emulsions.

Level

Take the use level from the supplier documentation for your lot.

Compatibility

The peptide is happiest in mild, water-rich bases. Strong acid exfoliants and very high levels of alcohol are poor company. If you combine it with other peptides, add each one on its own.

Product types that suit it

Forehead and frown-line serums, eye creams, smoothing primers, sheet-mask essences and light day creams. It is also a common upgrade for an existing hyaluronic serum.

Pairing ideas

Pentapeptide-18, Acetyl Octapeptide-3, sodium hyaluronate, glycerin and caffeine for eye products. Add each active separately and check clarity, odor and viscosity after each addition instead of premixing several actives in one beaker.

Example smoothing serum architecture

The level comes from the CoA, so no gram recipe is given. A dropper or pump bottle works well.

Claims

Describe expression lines that look softer and skin that looks smoother. Keep claims cosmetic and tied to appearance. Any before-and-after statement needs a test on the finished product, not on the raw material.

Testing the finished product

Run a stability check on the finished product at room temperature, at 40 °C and in a fridge for several weeks, and watch color, odor, clarity, viscosity and pH. Check the product in its final pack too, since pumps, droppers and jars expose it to air differently. A preservative challenge test on the final product is the standard step before launch.

Lot handling and storage

Record appearance and pH on arrival, compare them with the CoA, and keep the CoA with your batch records so each finished batch can be traced to its lot. Store tightly closed, cool and away from light, and respect the shelf life on the CoA.

Ordering

It is sold as a raw material for cosmetic formulation, not as a finished consumer product. Start with a small pack for bench trials and scale once your stability checks pass. It ships from Florida, usually within 1 to 2 business days, in the pack sizes shown above, and US shipping is free on orders of $50 or more.