TRX (Rh-Polypeptide-2) Powder

TRX (Rh-Polypeptide-2) at a glance

TRX Powder is a water-soluble powder with the INCI sh-Polypeptide-2 and CAS 52500-60-4. The sh prefix marks lab-made proteins that mirror signaling proteins naturally present in the body. In cosmetics, these ingredients appear in premium age-defying serums and creams. No use level appears in the supplier specification; the CoA and data sheet set the dose.

Working with protein actives

Proteins are delicate. Heat, strong acids or bases, high shear and some preservatives can affect them. Gentle processing, a skin-friendly pH and protective packaging help keep the product stable. Ask the supplier for guidance on compatible ingredients.

Product formats

Premium serums

Light water-based serums with a high-tech story.

Essences

Thin, watery products applied after cleansing.

Creams

Light creams with a peptide complex.

Eye products

Gels and light creams for the eye area.

Processing

Dissolve the powder completely in a small amount of water at room temperature. Add the solution to the batch during cool-down, below about 40 °C. Avoid prolonged heating and vigorous high-shear mixing after adding it. Check the final pH.

Good partners

Copper peptide GHK-Cu and Palmitoyl tripeptide-1 complete a peptide serum. Trehalose adds hydration. More lab-made peptides sit in the peptide powders section.

Testing

Run stability tests at several temperatures and check clarity, color and odor. Ask the supplier for data supporting any specific claim.

Claims

Premium peptide care; skin looks smoother and more radiant with regular use. Base specific claims on supplier data.

Characteristics

Form: powder. INCI: sh-Polypeptide-2. CAS: 52500-60-4. Solubility: water. Use level: supplier CoA.

Original recipe: peptide essence, 100 g

Distilled water 91.80 g, glycerin 3.00 g, trehalose 2.00 g, TRX powder 0.10 g, panthenol 1.00 g, sodium hyaluronate 0.10 g, phenoxyethanol and ethylhexylglycerin 1.00 g, sodium citrate 0.50 g, citric acid 0.50 g. Dissolve sodium hyaluronate and trehalose in water with glycerin, add panthenol, the preservative and the buffer, then the TRX solution at room temperature. Adjust the TRX level to the CoA.

Cold handling

Many protein actives are stored refrigerated. Check the CoA for storage temperature and let the container reach room temperature before opening to avoid condensation.

Labeling

Use the INCI name sh-Polypeptide-2 on the label. Explain the story in plain words on the front, such as a lab-made peptide for smoother-looking skin.

Lab tip

Use clean, dedicated tools when weighing small amounts of high-value peptides.

Lot records

Keep each CoA with the batch file and note the lot used.

Building a premium serum

High-tech protein actives deserve a clean, elegant base. Choose a light humectant system, a mild preservative and a fragrance-free or lightly scented profile. A short ingredient list helps the active stand out and makes the product easier to stabilize. Fill into airless pumps or amber dropper bottles.

Directions for users

Suggest applying a few drops morning and evening after cleansing, before a moisturizer. Regular use over several weeks is the usual recommendation for peptide products.

Supplier data

Ask for the protein content, the storage temperature and any test results, and keep them with the product file.

Lab hygiene

Work on a clean bench and close the container quickly to limit moisture uptake.

Record keeping

Note the storage temperature on arrival and the date the container was first opened, because protein actives can lose quality once exposed to air and moisture.

Storage

Store closed as the CoA directs, usually cold. Close the container after use.