FGF-1, Polypeptide 11 Powder

A recombinant polypeptide for biotech serums

FGF-1 is the trade label for a recombinant polypeptide of the acidic fibroblast factor class. Brands use it in ampoules and premium serums that tell a biotech renewal story. The US catalog INCI is sh-Polypeptide-11. CAS is N/A because no single published number has been confirmed for this listing. This page is the powder.

Not EGF or IGF

EGF BT is rh-Oligopeptide-1 and IGF powder is sh-Oligopeptide-2. TRX is sh-Polypeptide-2. Each has its own INCI. No FGF-1 solution is on our solution list. Compare dry options in our peptide powders.

Working with the powder

Dissolving

Weigh the powder on a calibrated balance, dissolve it completely in a small portion of the formula water before it meets the rest of the batch, and add that premix in cool-down, below 40 °C. Check that the premix is fully clear before you add it.

Compatibility

Keep it away from strong oxidizers and high-ionic-strength systems, such as products very rich in salts. A mild, water-rich base is the safest home.

Level

Take the use level from the supplier documentation for your lot.

Shear

Recombinant proteins are more fragile than short peptides, so keep shear low once it is in and stir with a paddle rather than a high-speed homogenizer.

Product types that suit it

Ampoules, light serums, sheet-mask essences and gel creams with few surfactants.

Pairing ideas

Sodium hyaluronate, glycerin, panthenol and niacinamide. Add each active separately and check clarity, odor and viscosity after each addition instead of premixing several actives in one beaker.

Example architecture

Water, glycerin, a sodium hyaluronate gel, the FGF-1 premix at the supplier level, a chelator and a mild preservative, filled into an airless pump. The level comes from the CoA, so no gram recipe is shown here.

Claims

Describe skin that looks fresher, smoother and more radiant with regular use. Keep claims cosmetic and tied to appearance. Any before-and-after statement needs a test on the finished product, not on the raw material.

Testing the finished product

Run a stability check on the finished product at room temperature, at 40 °C and in a fridge for several weeks, and watch color, odor, clarity, viscosity and pH. Check the product in its final pack too, since pumps, droppers and jars expose it to air differently. A preservative challenge test on the final product is the standard step before launch.

Lot handling and storage

Record appearance and pH on arrival, compare them with the CoA, and keep the CoA with your batch records so each finished batch can be traced to its lot. Keep the powder tightly closed and dry, since peptides pick up moisture from the air, and respect the shelf life on the CoA.

Labeling and documents

Write the INCI exactly as the CoA for your lot gives it, in the order the supplier lists it, and keep the CAS line the same as the CoA, including N/A or Mixture where that is what it says. Keep the CoA with your batch records. If your market needs an SDS or a full ingredient breakdown, ask for it before you scale so the paperwork matches the batch you buy.

Ordering

It is sold as a raw material for cosmetic formulation, not as a finished consumer product. Start with a small pack for bench trials and scale once your stability checks pass. It ships from Florida, usually within 1 to 2 business days, in the pack sizes shown above, and US shipping is free on orders of $35 or more.