Tripeptide-10 Citrulline Powder

What Tripeptide-10 Citrulline is

Tripeptide-10 Citrulline, CAS 960531-53-7, is a short synthetic peptide that includes citrulline, an amino acid naturally present in the skin's moisturizing factors. Supplier literature describes it as mimicking a fragment of decorin, a small proteoglycan that binds to collagen fibers and helps keep them evenly spaced and organized. The idea is easy to explain to shoppers: organized fibers, smoother and more supple-looking skin. This page sells the peptide as a powder by the gram.

Properties

The powder dissolves in water and forms a clear solution, so it suits clear serums and gels as well as emulsions. In finished products it is positioned for smoother texture, a more elastic and supple look and an improved feel of the skin surface. Because it targets a different part of the matrix story than palmitoyl peptides, it adds variety to multi-peptide products.

Applications

The record lists skin care for appearance-focused, moisturizing and restorative products and hair care. In skin care, typical products are firming serums, moisturizing creams, eye creams and neck creams. In hair care, brands use it in leave-in conditioners and scalp serums for a stronger, more supple feel. It combines well with Palmitoyl Pentapeptide-4 Powder and with 9837 Powder, another proteoglycan-themed peptide. See more in our peptide powders section.

How to dissolve and add it

Weigh the powder with a precise balance. Dissolve it fully in a small amount of distilled water until clear, then add the dissolved peptide to the cooled batch below 40 °C with gentle mixing. Avoid long heating afterwards. Take the use level from the supplier documentation for your lot.

A proteoglycan-themed duo

Decorin and lumican are both proteoglycans that organize collagen. Combining Tripeptide-10 Citrulline, linked to decorin, with Acetyl Tetrapeptide-9, linked to lumican, gives a coherent story for a firming serum. Dissolve each peptide separately, add them one after the other and keep each within its CoA range. Add a humectant for immediate comfort and a light gel texture for daily use. In hair care, the same peptide fits leave-in conditioners and scalp serums; add it after any cationic conditioning agents and check clarity, then present the product around hair that feels stronger and more supple.

Compatibility

Tripeptide-10 Citrulline is compatible with glycerin, hyaluronic acid, panthenol, niacinamide, amino acids, plant extracts and other peptides. It suits gels, serums, emulsions and leave-in hair products. Avoid strong acids, strong bases, oxidizers and long heating. Copper peptides belong in a separate product.

Characteristics

Form: powder. INCI: Tripeptide-10 Citrulline. CAS: 960531-53-7. Solubility: water. Addition point: cool-down after full dissolution.

Original recipe: supple skin serum, 100 g

Peptide premixes: Tripeptide-10 Citrulline Powder 0.02 g in distilled water 3.00 g; 9837 Powder 0.02 g in distilled water 2.00 g. Phase A: distilled water 87.06 g, glycerin 3.00 g, betaine 2.00 g, hydroxyethylcellulose 0.50 g; hydrate until clear. Phase B below 40 °C: both premixes, panthenol 1.00 g, sodium hyaluronate 0.10 g predissolved. Phase C: preservative 0.90 g, cucumber extract 0.40 g. Mix gently and adjust pH to about 6.0.

Record the lot number of Tripeptide-10 Citrulline Powder in your batch log so every production run can be traced back to its certificate of analysis.

Record the lot number in your batch log so every production run can be traced back to its certificate of analysis. Retain a small sample of each lot for at least the shelf life of the finished product, since it makes later quality questions much easier to answer.

Storage

Keep the powder sealed, cool and dry, away from light and humidity. Let it reach room temperature before opening. Note the date of first opening. Ships from Florida in gram packs.