Palmitoyl Tripeptide-28 Powder, IO

What this ingredient is

Palmitoyl Tripeptide-28 Powder is a peptide powder whose INCI is Palmitoyl Tripeptide-28. ECM stands for extracellular matrix, the network of collagen, elastin and glycosaminoglycans that gives skin its firmness and spring. The peptide is a short chain of three amino acids attached to palmitic acid, a design that improves its affinity for the skin surface. On this page it is sold as a dry powder by the gram. A CAS number is not verified in our records, so we list it as N/An and suggest the supplier SDS or CoA if your file requires one.

Properties

Palmitoyl Tripeptide-28 belongs to the family of matrix-themed signal peptides. Brands present it as an ingredient that helps skin look firmer, more lifted and more resilient, particularly in mature or stressed-looking skin. The powder dissolves in water, which makes it suitable for clear serums. Because it is a pure active, it is used at low levels, so a small pack covers many finished units.

Applications

The supplier record lists firming creams and serums, modeling lifting fluids, serums for mature and damaged-looking skin, restorative products after salon procedures and products that help keep skin looking youthful. Typical finished goods are lifting serums, firming night creams, neck creams and professional leave-on cosmetic serum masks. It works well with other matrix peptides such as Palmitoyl Tripeptide-38 Powder and with humectants like Low Molecular Weight Hyaluronic Acid 10-20 kDa. Browse more dry actives in our peptide powders section.

How to dissolve and add it

Weigh the powder with a balance reading to 0.001 g. Dissolve it fully in a small amount of distilled water until clear, then add the dissolved peptide to the batch during cool-down, below 40 °C, with gentle mixing. Avoid holding the batch at high temperature afterwards. The card does not give an use percentage; follow the CoA and keep the finished pH in a mild range close to skin.

Products for after salon procedures

Aestheticians often sell take-home products that support comfort after peels, microneedling-style cosmetic sessions or intensive facials. These products need mild bases, no fragrance, a preservative suitable for sensitive skin and comforting partners such as panthenol and allantoin. This ingredient fits this concept as the firming element. Clear usage instructions and small pack sizes suit professional channels.

Compatibility

Palmitoyl Tripeptide-28 is compatible with glycerin, hyaluronic acid, panthenol, niacinamide, allantoin, plant extracts and other peptides. It suits gels, serums and oil-in-water emulsions. Avoid strong acids, strong bases, oxidizers and long heating. Copper peptides are better placed in a separate product. Add several peptides one at a time and check for haze after each.

Characteristics

Form: powder. INCI: Palmitoyl Tripeptide-28. CAS: N/A, verify on the supplier SDS or CoA. Solubility: water. Addition point: cool-down after full dissolution.

Original recipe: lifting serum, 100 g

Peptide premix: Palmitoyl Tripeptide-28 Powder 0.02 g dissolved in distilled water 3.98 g. Phase A: distilled water 86.40 g, glycerin 3.00 g, propanediol 2.00 g, hydroxyethylcellulose 0.50 g; hydrate until clear. Phase B below 40 °C: the peptide premix, Low Molecular Weight Hyaluronic Acid 10-20 kDa 0.10 g predissolved in a little water, panthenol 1.00 g, niacinamide 2.00 g. Phase C: preservative 1.00 g. Mix gently, adjust pH to about 5.8 and fill into an airless pump.

Record the lot number in your batch log so every production run can be traced back to its certificate of analysis. Retain a small sample of each lot for at least the shelf life of the finished product, since it makes later quality questions much easier to answer.

Storage

Keep the powder sealed, cool and dry, away from light and humidity. Let the container reach room temperature before opening. Ships from Florida in gram packs.