B-series liposome

B-series liposome at a glance

B-series liposome is a vitamin complex in liposomes. A full B group set, vitamins B1, B3, B5, B6 and B7, is combined with vitamin F, the glyceryl esters of linoleic and linolenic acids, and with resveratrol, an antioxidant from grapes. All of this is enclosed in vesicles made of phosphatidylcholine, the main lipid of lecithin, in a glycerin base. The INCI lists Phosphatidylcholine, Glycerin, Thiamine, Niacinamide, Panthenol, Pyridoxine, Biotin, Glyceryl Linoleate, Glyceryl Linolenate and Resveratrol. The liquid is opalescent, mixes with water, has a pH of 3.6 to 7.4 and is used at 2 to 10%. It comes from Spain.

What each vitamin brings

Niacinamide and panthenol

Vitamin B3, niacinamide, is one of the most popular actives in skin care, known for a more even looking tone, smaller looking pores and a stronger barrier. Vitamin B5, here as its pantothenic form, is the classic moisturizing and comfort vitamin.

Thiamine, pyridoxine and biotin

Vitamin B1 thiamine and vitamin B6 pyridoxine are linked to the energy and balance of the skin, and B6 is often used in care for oily skin. Vitamin B7 biotin is the best known vitamin for hair and nails and also supports a smooth skin surface.

Vitamin F and resveratrol

Linoleic and linolenic acids, known together as vitamin F, are essential fatty acids that the skin uses to build its barrier lipids. Resveratrol adds antioxidant protection against daily environmental stress.

Why liposomes

Liposomes are tiny spheres made of the same type of lipids as cell membranes. They hold water-soluble vitamins in their core and fatty acids in their walls, so one carrier can deliver both. The lecithin also leaves a soft, conditioning feel on the skin. For formulators building consumer-facing cosmetics, liposome is a familiar technology word that suggests advanced care.

How to formulate

Add the liposomes at cool-down, below about 40 °C, after any homogenization, and stir slowly. Avoid high levels of ethanol and strong surfactants, which can break the vesicles. The pH range of 3.6 to 7.4 covers almost all face care. Use 2 to 5% in daily creams and gels and up to 10% in intensive serums. The vitamin story can be extended with niacinamide as a separate active for a higher B3 level, and with biotin liposomes in a hair and scalp line. Explore more vitamin actives in the cosmetic actives section.

Product ideas

appearance-focused cosmetic serums and gels, creams for mature and tired looking skin, balancing fluids for oily skin, moisturizing day creams, vitamin booster ampoules and sheet masks are the main uses. A multi vitamin serum with a clear label story is the simplest and most effective concept.

Sample recipe: vitamin B booster gel, 100 g

Distilled water 84.20 g, glycerin 3.00 g, propanediol 3.00 g, hydroxyethylcellulose 0.80 g, B-series liposome 6.00 g, preservative 1.00 g, panthenol 1.00 g, sodium hyaluronate 0.20 g, citric acid solution 0.80 g. Hydrate sodium hyaluronate and the cellulose in water, add glycerin, propanediol and panthenol, then below 40 °C add the liposomes and the preservative with slow stirring, and adjust to about pH 5.5.

Labeling and claims

On the ingredient list each vitamin appears under its own INCI name, which gives a long, rich label. Claims can speak of energized, smoother and more even looking skin, smaller looking pores and a more comfortable, hydrated feel. A short consumer panel over four weeks is a practical way to support such claims.

Stability

Vitamins are sensitive to light and air. Pack the finished product in opaque or airless containers and run a stability test at 40 °C to check color and odor. A slight change in color of the opalescent liquid between lots is normal.

Storage

Store in a cool, dark place in a tightly closed container. A certificate of analysis comes with every lot.