
Acetyl Hexapeptide-8 Liposome
$19.99

SKU: TM19043007
INCI: Sodium Hyaluronate (and) Hydrolyzed Sodium Hyaluronate (and) Sodium Acetylated Hyaluronate (and) Sodium Hyaluronate Crosspolymer (multi-molecular-weight system; confirm exact composition on supplier CoA).
Usage Rate: Typical: 0.5–2.0% of the supplied solution in leave-on serums/essences; 0.2–1.0% in lightweight gels and emulsions. Start at 1.0% and adjust for feel and viscosity.
Liquid sizes (US · metric)
Pricing available on request — wholesale quotes by packaging size.
4D Hyaluronic Acid, widely sold under the trade name Hymagic-4D, is a next-generation hydration system built around four distinct molecular weights of hyaluronic acid working together in a single ingredient. Where a conventional hyaluronic acid raw material delivers a single chain length — and therefore acts at a single depth — this 4D system layers ultra-low, low, medium, and high molecular-weight fractions so that the finished formula hydrates from the outermost surface of the stratum corneum down to the deeper, living layers of the epidermis. The result is the "4D" effect: hydration in space (different depths) and in time (immediate surface smoothing plus longer-lasting reservoir hydration).
Hyaluronic acid is a glycosaminoglycan that occurs naturally in human skin, where it binds and holds water — up to roughly a thousand times its own weight. As we age, both the quantity and quality of native hyaluronic acid decline, contributing to dryness, loss of bounce, and the appearance of fine lines. Topically applied hyaluronic acid cannot fully replace what the dermis produces, but a well-designed multi-weight system can meaningfully improve the skin's water content, barrier feel, and visible smoothness. The high molecular-weight fraction forms a breathable, moisture-locking film on the surface that reduces transepidermal water loss and gives an immediate silky, cushioned feel. The medium and low fractions penetrate progressively deeper, drawing water into the upper epidermal layers and supporting a plumper, more even surface. The ultra-low fraction is small enough to reach the deeper epidermis, where it can support the skin's own hydration dynamics and contribute to a longer-lasting, "filled-from-within" appearance.
For formulators, this multi-weight design is the core selling point. A single high molecular-weight HA can feel tacky and sit on the surface; a single low molecular-weight HA penetrates but offers little immediate sensorial payoff and, at very high use levels, has been discussed in the literature for pro-inflammatory potential. By blending weights, Hymagic-4D-type ingredients deliver both the instant cosmetic elegance consumers expect and the deeper, cumulative hydration that supports a long-term claims story. It is exceptionally versatile: it slots into essences, serums, ampoules, sheet-mask serums, lightweight gels, emulsions, eye creams, after-sun products, and post-procedure soothing formulas.
In use, 4D Hyaluronic Acid is typically supplied as a clear, water-soluble liquid concentrate (it disperses readily in water and glycols), which makes it straightforward to incorporate into the water phase of a formulation without heating. Because hyaluronic acid is a humectant, pairing it with an occlusive or emollient system helps "seal" the drawn-in water and prevents the humectant from pulling moisture from the skin in very dry, low-humidity environments. It performs beautifully alongside other hydration and barrier actives such as glycerin, panthenol, betaine, trehalose, ceramides, and niacinamide, and it is a natural partner for peptides and antioxidants in a modern "hydrate-plus-treat" serum.
The consumer benefits translate cleanly into marketing claims: immediate plumping and smoothing, a dewy and supple finish, reduced appearance of fine dehydration lines, improved makeup application over a smoother canvas, and long-lasting comfort. Because the system is non-irritating and suitable for essentially all skin types — including sensitive, oily, combination, and compromised barriers — it is an easy "hero hydrator" anchor for a launch range. It is also an excellent supporting actor: a low-tack hydration base that improves the sensorial profile of treatment serums built around retinoids, acids, vitamin C, or peptides.
From a stability and handling standpoint, hyaluronic acid solutions are sensitive to strong oxidizers, very low pH, high electrolyte loads, and microbial contamination, so robust preservation and a well-chosen, skin-friendly pH (broadly in the mildly acidic to neutral range typical of leave-on skincare) are important. The ingredient is shear- and heat-tolerant enough for normal cold-process incorporation, and it does not require specialized equipment. Its clarity and low color make it suitable for transparent, premium-looking serums and essences where visual elegance is part of the product promise.
In short, 4D Hyaluronic Acid (Hymagic-4D) is a workhorse hydration active that punches above a basic single-weight HA. It gives formulators a single, elegant ingredient that delivers multi-depth, multi-duration moisturization with an excellent skin feel, broad compatibility, and a compelling, science-forward claims platform — making it a strong foundation for serums, essences, masks, and lightweight moisturizers in a launch collection.
It combines four molecular weights so it hydrates at multiple skin depths and over a longer time, rather than acting at a single level.
Yes — it is non-comedogenic, lightweight, and generally well tolerated across skin types.
Commonly 0.5–2% of the supplied solution in serums; begin around 1% and adjust for texture.
No. It is cold-processable; add to the water phase and mix until uniform.
Yes. It is broadly compatible and often used as a hydrating base that improves the feel of active serums.